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Table 2 National Health and Medical Research Council (NHMRC) levels of evidence

From: Chiropractic care for paediatric and adolescent Attention-Deficit/Hyperactivity Disorder: A systematic review

Level

Intervention Studies

I

Systematic review of level II studies

II

Randomised controlled trial

III-I

Pseudo-randomised controlled trial (i.e. alternate allocation or some other method)

III-2

Comparative study with concurrent controls:

 

•Non-random, experimental trial

 

•Cohort study

 

•Case-control study

 

•Interrupted time series with a control group

III-3

Comparative study without concurrent controls:

 

•Historical control study

 

•Two or more single arm study

 

•Interrupted time series without a parallel control group

IV

Case series with either post-test or pre-test/post-test outcomes

  1. NB. Adapted from NHMRC Levels of evidence [58]