Reference | Year | Authors | Title | Location | Setting | n° of subjects | n° males | n° females | Ages | Treatment groups | How was pain produced | How was pain measured | When was pain measured | Description of study subjects | Approval ethics committee |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
[37] | 2011 | Josue Fernández-Carnero, Joshua A. Cleland and Roy La Touche Arbizu | Examination of motor and hypoalgesic effects of cervical vs thoracic spine manipulation in patients with lateral epicondyalgia: a clinical trial. | Spain | University | 18? | 8 | 9 | 44.8 SD, 9.2 (30–60) | - Cervical manipulation | Pressure | Electronic digital algometer | Before and after | Faculty of the Health Science | Yes |
- Thoracic manipulation | |||||||||||||||
[42] | 2011 | V. Maduro de Camargo, F. Alburquerque-Sendín, F. Bérzin, Vinicius Cobos Stefanelli, D. P. Rodrigues de Souza and C. Fernández-de-las-Peñas, | Immediate effects on electromyographic activity and pressure pain thresholds after a cervical manipulation in mechanical neck pain: a randomized controlled trial. | Brazil | University | 37 | 21 | 16 | 18 – 42 | - SMT C5-C6 | Pressure | Analogue algometer | Before and after | University workers | Yes |
- Control | |||||||||||||||
[23] | 2011 | Mark D. Bishop, Jason M. Beneciuk, Steven Z. George; | Immediate reduction in temporal sensory summation after thoracic spinal manipulation. | USA | University | 90 | 24 | 66 | 22.9 + −2.7 | - SMT | T° and pressure | Algometer | Before and Immediately after | Students | No |
- Cervical exercises | |||||||||||||||
- Control | |||||||||||||||
[28] | 2010 | Benjamin Soon, Annina B. Schmid, Elias J. Fridriksson, Elizabeth Gresslos, Philip Cheong and Anthony Wright; | A crossover study on the effect of cervical mobilization on motor function and pressure pain threshold in pain-free individuals. | Australia | University | 24 | 13 | 11 | 34 +/−12 | - Mobilization | Pressure | Digital algometer | Before and after | Students | Yes |
- Manual contact control | |||||||||||||||
- Control | |||||||||||||||
[29] | 2010 | Oliveira-Campelo NM, Rubens-Rebelatto J, Martín-Vallejo FJ, Alburquerque-Sendí N F, Fernández-de-Las-Peñas C. | The immediate effects of atlanto-occipital joint manipulation and suboccipital muscle inhibition technique on active mouth opening and pressure pain sensitivity over latent myofascial trigger points in the masticatory muscles. | Spain | Osteopathic school and university | 122 | 31 | 91 | 18-30 | - Manipulation | Pressure | Mechanical algometer | Before and 2 min post treatment | Students | Yes |
Brazil | - Soft tissue | ||||||||||||||
- Control | |||||||||||||||
[44] | 2010 | Elaine Willett, Clair Hebron and Oliver Krouwel | The initial effects of different rates of lumbar mobilizations on pressure pain thresholds in asymptomatic subjects. | UK | University | 30 | 8 | 22 | 33.05 (18–57) | - 2 Hz | Pressure | Electronic algometer | Base | 11 naive physiotherapists 19 non naive | Yes |
- 1 Hz | + 48 h | ||||||||||||||
- Quasi stable | + 48 h | ||||||||||||||
[38] | 2009 | P. Mansilla-Ferragut, C. Fernández-de-las Peñas, F Alburquerque-Sendin, J. A. Cleland and JJ Boscá-Gandia | Immediate effects of atlanto-occipital joint | Spain | Osteopathic school | 37 | 0 | 37 | 35 +/−8 | - SMT | Pressure | Mechanical algometer | Before and after | Volunteers, general population | Yes |
Manipulation on active mouth opening and pressure pain sensitivity in women with mechanical neck pain. | |||||||||||||||
- Control | |||||||||||||||
[30] | 2009 | Oliver Thomson, Lesley Haig, Hazel Mansfield | The effects of high-velocity low-amplitude thrust manipulation and mobilization techniques on pressure pain threshold in the lumbar spine. | Sweden | Stockholm College Osteopathic | 50 | 29 | 21 | 27 | - unilateral HVLAT | Pressure | Pressure algometer | Before and after | Students | Yes |
UK | School British College | - Spinal lumbar mobilization | |||||||||||||
- Sham laser procedure | |||||||||||||||
[43] | 2009 | Oliver Krouwel , Clair Hebron, Elaine Willett | An investigation into the potential hypoalgesic effects of different amplitudes of PA mobilizations on the lumbar spine as measured by pressure pain thresholds. | UK | University | 30 | 9 | 21 | 26,43 (SD 4,92) | - Large oscillation (force applied) | Pressure | Digital algometer | Baseline before and + 24, + 24 | 13/30 physiotherapy naives | Yes |
- Small oscillation quasi static | |||||||||||||||
[18] | 2009 | Joel E. Bialosky, Mark D. Bishop, Michael E. Robinson, Giorgio Zeppieri Jr, Steven Z. George | Spinal manipulative therapy has an immediate effect on thermal pain sensitivity in people with low back pain: a randomized controlled trial. | USA | University | 36 | 10 | 26 | 32.38 (12.63) | - SMT | T° | Numerical scale | Before and Immediately after | Students with low back pain | No |
- Biking | |||||||||||||||
- Back extension exercise | |||||||||||||||
[19] | 2008 | J. Fernández-Carnero, Cesar Fernández-de-las-Peñas, and Joshua A. Cleland | Immediate hypoalgesic and motor effects after a single cervical manipulation in subjects with lateral epicondyalgia. | Spain | Universities and Osteopathic school Madrid | 10 | 5 | 5 | 42 (SD6) | - Manipulative session | T° and pressure | Electronic algometer | Before and after | Patients | Yes |
USA | - Manual contact intervention | ||||||||||||||
[39] | 2008 | C. Fernández-de-las-Peñas, C. Alonso-Blanco, J. A. Cleland, C. Rodriguez-Blanco and F.Alburquerque-Sendin | Changes in pressure pain thresholds over C5-C6 zygapophyseal joint after a cervicothoracic junction manipulation in healthy subjects. | Spain | Universities and Osteopathic school Madrid | 30 | 13 | 17 | 26 (SD 5) | - Manipulative thrust right side C7-T1 | Pressure | Algometer | Before and after | General population | Yes |
- Manipulative thrust left side C7-T1 | |||||||||||||||
USA | - Sham-manual procedure | ||||||||||||||
[20] | 2007 | M. Ruiz-Sáez, C. Fernández-de-las-Peñas, C. Rodriguez Blanco, R. Martinez-Segura and R. Garcia-León | Changes in pressure pain sensitivity in latent myofascial trigger points in the upper trapezius muscle after a cervical spine manipulation in pain-free subjects. | Spain | Osteopathic school | 72 | 27 | 46 | 31 (SD10) | - Manipulative | Pressure | Mechanical algometer | Baseline before 1, 5 and 10 min after | Volunteers, general population | Yes |
- Sham-manual | |||||||||||||||
[31] | 2007 | Fernández-de-las-Peñas C, Pérez-de-Heredia M, Brea-Rivero M, Miangolarra-Page JC. | Immediate effects on pressure pain threshold following a single cervical spine manipulation in healthy subjects. | Spain | Universities | 15 | 7 | 8 | 21 + −2 | - Manipulation | Pressure | Mechanical algometer | Before 5 min after intervention | Students | Yes |
- Placebo | 3 sessions separated by 48 h | ||||||||||||||
- Control | |||||||||||||||
[34] | 2007 | Hamilton L, Boswell C, Fryer G | The effects of high-velocity, low-amplitude manipulation and muscle energy technique on suboccipital tenderness. | Australia | University | 90 | 29 | 61 | 23 +/−5 | - SMT (C0- C1) | Pressure | Electronic algometer | Before and after | Students | Yes |
- Muscle energy technique | |||||||||||||||
- Control | |||||||||||||||
[36] | 2006 | George SZ, Bishop MD, Bialosky JE, Zeppieri G Jr, Robinson ME. | Immediate effects of spinal manipulation on thermal pain sensitivity: an experimental study. | USA | University | 60 | 20 | 40 | 24.03(SD 3.2° | - SMT | T° | Medoc neurosensory analyzer | Before and 5 min after | Students | Yes |
- Lumbar ext exercise | |||||||||||||||
- Bicycle riding | |||||||||||||||
[40] | 2004 | P.Mohammadi, A. Gonsalves, Chris Tsai, T. Hummel and Thomas Carpenter | Areas of capsaicin-induced secondary hyperalgesia and allodynia are reduced by a single chiropractic adjustment: preliminary study. | USA | Universities | 20 | 14 | 6 | 27 (21–37) | - SMT | Cutaneous capsaicin | Visual Analogue Scale | Before and 20 min after after | Healthy volunteers, mostly naive to SMT | Yes |
Germany | - Non-SMT | ||||||||||||||
[35] | 2004 | Fryer G, Carub J, McIver S. | The effect of manipulation and mobilization on pressure pain thresholds in the thoracic spine. | Australia | University | 96 | 39 | 57 | 19-34 | - SMT T2-T4 | Pressure | Electronic algometer | Before and after | Students | Yes |
- Mobilisation | |||||||||||||||
- Control | |||||||||||||||
[21] | 2001 | M. Sterling, G. Jull, A. Wright | Cervical mobilization: concurrent effects on pain, sympathetic nervous system activity and motor activity. | Canada | University | 30 | 14 | 16 | 35.7 (SD 14.92) | - SMT | Pressure / T° | Visual Analogue Scale, electronic algometer | Before and after | Patients pain +3 months C5/6 | Yes |
- Placebo | |||||||||||||||
- Control | |||||||||||||||
[32] | 1998 | Bill Vicenzino, David Collins and Anthony Wright | An investigation of the Interrelationship between manipulative therapy-Induced hypoalgesia and sympathoexcitation. | Australia | University | 24 | 11 | 13 | 49.0 (27–70) | - Mobilization C5-C6 | Pressure / T° | Visual Analogue Scale, digital algometer | Before and after | Patients epicond 6.2 +/− 5.1 months | Yes |
- Manual contact placebo | |||||||||||||||
- Nothing | |||||||||||||||
[33] | 1996 | Bill Vicenzino, David Collins and Anthony Wright | The initial effects of a cervical spine manipulative physiotherapy treatment on the pain and dysfunction of lateral epicondyalgia. | Australia | University | 15 | 7 | 8 | 44 +/−2 | - Treatment | Pressure | Visual Analogue Scale digital algometer | Before and after | Patients epicond 8 +/− 2 months | Yes |
- Placebo | |||||||||||||||
- Control | |||||||||||||||
[41] | 1984 | Terrett AC, Vernon H. | Manipulation and pain tolerance. A controlled study of the effect of spinal manipulation on paraspinal cutaneous pain tolerance levels. | Canada | Chiropractic college | 50 | ? | ? | 28.6 | - Thoracic manipulation | Electrical induction | Thresholds | Before and after | Chiropractic students | No |
- Control group |