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Table 7 Comparison of evidence in UK evidence report and current review for non-musculoskeletal conditions

From: Clinical effectiveness of manual therapy for the management of musculoskeletal and non-musculoskeletal conditions: systematic review and update of UK evidence report

Condition Intervention UK evidence report evidence New/additional evidence New evidence?
   Inconclusive Moderate High Inconclusive Moderate High  
Asthma Spinal manipulation   Negative   Unclear    yes
  Osteopathic manual therapy Favourable    Favourable    no
  Cranio-sacral therapy     Favourable    yes
Attention deficit hyperactivity disorder Osteopathic treatment     Unclear    yes
Cancer care Chiropractic care     Unclear    yes
  Massage including myofascial release/strain/counterstrain      Positive   yes
  Manipulation in osteosarcoma      Negative   yes
Cerebral palsy Osteopathic manual therapy (cranio-sacral, cranial, myofascial release)     Unclear    yes
Chronic fatigue syndrome/myalgic encephalomyelitis Osteopathic manual therapy     Favourable    yes
Chronic pelvic pain • interstitial cystitis/painful bladder syndrome/chronic prostatitis Myofascial therapy     Favourable    yes
• chronic pelvic pain in women Distension of painful pelvic structures     Favourable    yes
• chronic prostatitis/chronic pelvic pain/female urination disorders Osteopathic manual therapy     Favourable    yes
Cystic fibrosis Mobilisation     Unclear    yes
Paediatric dysfunctional voiding Osteopathic manual therapy     Favourable    yes
Paediatric nocturnal enuresis Spinal manipulation Favourable    Favourable    no
Infant colic Spinal manipulation   Negative   Favourable    yes
  Cranial osteopathic manual therapy Favourable    Favourable    no
Dysmenorrhoea Spinal manipulation   Negative    Negative   no
Premenstrual syndrome Spinal manipulation Unclear    Unclear    no
Menopausal symptoms Fox’s low force osteopathic technique plus cranial techniques     Favourable    yes
Gastrointestinal disorders reflux disease, duodenal ulcer Spinal manipulation     Unclear    yes
• irritable bowel syndrome Osteopathic manual therapy     Favourable    yes
Hypertension stage 1 hypertension Spinal manipulation added to diet   Negative    Negative   no
  Upper cervical (NUCCA) spinal manipulation Favourable    Favourable    no
  Instrument assisted spinal manipulation Unclear    Unclear    no
  Osteopathic manual therapy     Unclear    yes
  Gonstead full spine chiropractic care     Unclear    yes
Intermittent claudication Osteopathic manual therapy     Favourable    yes
Venous insufficiency Myofascial release manual therapy combined with kinesiotherapy     Favourable    
Insomnia Spinal manipulation     Unclear    yes
Otitis media Osteopathic manual therapy Unclear    Unclear    no
Parkinson’s disease Osteopathic manual therapy     Favourable    yes
Pneumonia in elderly adults Osteopathic manual therapy Favourable    Favourable    no
Chronic obstructive pulmonary disease in elderly adults Osteopathic manual therapy     Favourable    yes
Back pain during pregnancy Spinal manipulation     Favourable    yes
Care during labour/delivery Spinal manipulation     Unclear    yes
Care of preterm infants Physiotherapeutic/osteopathic manual therapy     Unclear    yes
Surgery rehabilitation Osteopathic manual therapy     Favourable    yes
Stroke rehabilitation Mobilisation     Unclear    yes
Systemic sclerosis McMennell joint manipulation     Unclear    yes