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Table 3 Mean baseline clinical characteristics

From: A biopsychosocial approach to primary hypothyroidism: treatment and harms data from a randomized controlled trial

Outcome measure   Treatment Placebo
  Normal range Median (Min, Max) Mean (SD) Median (Min, Max) Mean (SD)
Thyroid function tests:      
 TSH (mIU/L) 0.40–3.50 0.96 (0.00, 55.77) 2.98 (8.39)a 1.34 (0.01, 7.30) 1.85 (1.76)
 FT4 (pmol/L) 9.0–19.0 15.00 (7.00, 26.00) 15.09 (3.22) 14.20 (3.80, 24.50) 14.51 (3.91
 FT3 (pmol/L) 2.6–6.0 4.06 (2.80, 7.45) 4.13 (0.80) 3.80 (3.00, 5.73) 3.95 (0.64)
DASS Scores:      
 Depression 0–9 6.50 (0.00, 29.00) 9.43 (8.60) 6.00 (0.00, 41.00) 7.85 (8.52)
 Anxiety 0–7 6.00 (0.00, 19.00) 6.79 (5.13) 4.00 (0.00, 30.00) 6.27 (7.73)
 Stress 0–14 13.00 (3.00, 35.00) 13.71 (8.28) 11.00 (2.00, 38.00) 12.76 (8.53)
SF-36v2 Scores: Normal Mean (SD) Median (Min, Max) Mean (SD) Median (Min, Max) Mean (SD)
 Physical functioning 50 ± 3 (10) 52.82 (25.46, 57.03) 48.06 (8.36) 50.72 (29.68, 57.03) 48.66 (7.72)
 Role physical 50 ± 3 (10) 49.51 (22.57, 56.85) 48.85 (8.60) 51.96 (17.67, 56.85) 46.32 (11.25)
 Bodily pain 50 ± 3 (10) 46.06 (24.08, 62.12) 49.97 (9.87) 46.06 (24.08, 62.12) 46.53 (9.43)
 General health 50 ± 3 (10) 45.31 (23.38, 57.70) 43.72 (11.26) 45.78 (23.78, 62.47) 45.16 (9.71)
 Vitality 50 ± 3 (10) 39.60 (23.99, 58.33) 40.15 (8.88) 41.16 (20.87, 58.33) 41.68 (10.33)
 Social functioning 50 ± 3 (10) 45.94 (13.22, 56.86) 42.09 (12.49) 45.94 (13.22, 56.85) 41.12 (12.82)
 Role emotional 50 ± 3 (10) 48.10 (20.89, 55.88) 44.78 (10.71) 44.22 (20.89, 55.88) 43.58 (10.96)
 Mental health 50 ± 3 (10) 44.38 (21.85, 61.27) 43.79 (11.04) 47.19 (16.22, 58.46) 43.03 (11.62)
 Physical component summary 50 ± 3 (10) 50.46 (30.08, 61.73) 48.27 (7.76) 51.39 (16.70, 59.78) 48.45 (9.54)
 Mental component summary 50 ± 3 (10) 42.59 (16.70, 60.18) 41.10 (11.49) 41.59 (16.40, 61.35) 40.79 (12.71)
  Normal Range Median (Min, Max) Mean (SD) Median (Min, Max) Mean (SD)
 Resting temperature (°C) 35.5–37.03 35.8 (32.8, 37.0) 35.6 (0.9) 35.6 (33.4, 36.6) 35.6 (0.7)
 Resting heart rate (bpm) 75–85 64 (30, 86) 65.7 (9.6) 64 (44, 86) 63.9 (11.3)
  1. The SF-36v2 scores are based on the norm based scoring system (NBS) which is based on a mean score with a normal range between 47 and 53 NBS points. Resting temperature and resting heart rate data were analysed based on ‘Day 1’ dairy entries
  2. aStrongly influenced by one person with very high TSH
  3. DASS Depression, Anxiety, Stress Score, NET Neuro-Emotional Technique, TSH Serum thyroid stimulating hormone, FT4 Free thyroxine, FT3 Free triiodothyronine, SF-36v2 Short Form-36 Version 2, Min minimum, Max Maximum, SD standard deviation