1st Author Year Journal | All studies included | Clinical research studies with appropriate or potentially appropriate study design to investigate an effect or benefit of Functional Neurology approach | |||||||
---|---|---|---|---|---|---|---|---|---|
-Design -Design appropriate to investigate effect or benefit of intervention? | If design was not appropriate, major methodological considerations (“NA” for appropriate or potentially appropriate study design) | Were study subjects stated to be: -Blind to treatment allocation? (NA if no sham) -Naïve to types of intervention? | -Was a random allocation reported? -Was it stated that this was concealed? (NA if no random allocation) | Were interventions well described? | Was the assessor reported to be blind? | Outcome measure reported to be reliable or reproducible? | Was the person who analyzed the data stated to be blind? | Were losses or exclusions reported or obvious in results, tables or graphs? | |
Malkowicz 2006 [20] Intern J Neuroscience | Retrospective study of clinical database with external control group (from previously published study) -No | In order to investigate the effect of intervention, it would be necessary to include a concomitant control group to ensure that the two groups are similar and assessed at similar interval(s). | |||||||
Daubeny 2010 [21] Int J Disabil Hum Dev | -Randomized controlled trial -Yes | NA | -No -No | -Yes -No | Yes | Yes | No | No | Yes |
Leisman 2010a [22] Int J Disabil Hum Dev | -Two randomized controlled trials (?) -Yes | NA | -NA -No | -Yes -No | Yes | No | No | No | No |
Leisman 2010b [23] Int J Adolesc Med Health | -Case series from multiple clinics (?) or Multicenter outcome study (?)* -No | In order to investigate an effect, a control group would be needed. | |||||||
Carrick 2011 [16] Funct Neurol Rehabil Ergon | -Outcome study -No | In order to investigate an effect or benefit, a control group would be needed. | |||||||
Castellanos 2012 [24] Funct Neurol Rehabil Ergon | -Outcome study with healthy untreated control group at baseline -No | In order to investigate effect or benefit, a similar control group subjected to another intervention would be needed. | |||||||
Carrick 2013 [17] Funct Neurol Rehabil Ergon | -Four arms randomized trial (?) -Potentially | NA | -NA -No | -Yes -No | Yes | No | No | No | No |
Sullivan 2013 [18] Funct Neurol Rehabil Ergon | -Prospective case series with sham treatment in 3/13 cases -Potentially | NA | -No -No | -No -NA | Yes | No | No | No | Yes |
Bousquet 2015 [19] Funct Neurol Rehabil Ergon | -Outcome study -No | In order to investigate an effect, a control group would be needed. |