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Table 1 Clinical trial populations and interventions

From: Cost-effectiveness of spinal manipulation, exercise, and self-management for spinal pain using an individual participant data meta-analysis approach: a study protocol

  Population Interventions
Condition Sample Age Group 1 Group 2 Group 3
Pre-dates CT.gov [29] Chronic neck pain 191 20–65 SMT + ET ET SMT
NCT00269360 [22] Chronic neck pain 270 18–65 SMT + ET ET SC
NCT00269308 [23] Chronic neck pain 241 65+ SMT + SC ET + SC SC
NCT00029770 [28] Acute neck pain 272 18–65 SMT SC Medication
NCT00269347 [24] Chronic low back pain 301 18–65 SMT ET SC
NCT00269321 [25] Chronic low back pain 240 65+ SMT + SC ET + SC SC
NCT00494065 [26] Chronic back-related leg pain 192 21+ SMT + SC SC
NCT01096628 [27] Chronic low back pain 184 12–18 SMT + ET ET
  1. CNP chronic neck pain, ANP acute neck pain, CLBP chronic low back pain, BRLP back related leg pain, SMT spinal manipulation therapy, ET exercise therapy, SC self-care