From: Manual therapy for chronic migraine: a pragmatic randomised controlled trial study protocol
Primary Outcomes | Measurement Instrument (validity) |
Migraine-related disability | Headache Impact Test (HIT 6) [54] |
Secondary Outcomes | Measurement Instrument |
Quality of Life | Migraine Specific Quality of Life Questionnaire (MSQ. V2.1)[59] |
Use of abortive migraine medications | 1.1.11.1.11.1.1Diary [69] |
Percentage of participants with reduction in headache frequency (days per month) of greater than 50% | |
Number of headache free days | |
Stress | |
Stress | Perceived Stress Questionnaire (PSS) [80] |
Stress | Brief Cope [81] |
Anxiety | State and Trait Anxiety Inventory (STAI-6) [63] |
Anxiety & Depression | Hospital Anxiety and Depression Scale (HADS) [82] |
Cutaneous Allodynia | Allodynia Symptom Checklist (ASC) [83] |
Cutaneous Allodynia | |
Patient Reported Outcome Measure | Patient Global Impression of Change Scale (PGICS) [85] |