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Table 5 Correlation coefficients for changes from baseline between cardiovascular autonomic outcomes and PPT in an RCT on spinal manipulation

From: The effect of a single spinal manipulation on cardiovascular autonomic activity and the relationship to pressure pain threshold: a randomized, cross-over, sham-controlled trial

OutcomesLog local PPT (kPa) N = 41Distal PPT (kPa) N = 37
Post 1 − BaselinePost 2 − BaselinePost 3 − BaselinePost 1 − BaselinePost 2 − BaselinePost 3 − Baseline
RRi (ms)SM− 0.021− 0.0030.012− 0.332− 0.0710.097
N = 41Sham− 0.237− 0.168− 0.0980.014− 0.0650.103
Log HF-HRV (ms2)SM− 0.2120.073− 0.034− 0.0670.0070.070
N = 41Sham− 0.124− 0.028− 0.184− 0.038− 0.0620.047
HF normalized unitSM− 0.266− 0.049− 0.058− 0.037− 0.0130.211
N = 41Sham− 0.0870.065− 0.167− 0.308− 0.026− 0.300
Log LF-HRV (ms2)SM0.1200.1260.077− 0.012− 0.015− 0.127
N = 41Sham− 0.010− 0.2050.1340.220− 0.0200.451
Log LF/HFSM0.2960.0450.1160.056− 0.020− 0.200
N = 41Sham0.079− 0.0830.2190.2620.0360.376
Log RMSSD (ms)SM− 0.2040.1610.086− 0.1020.0150.046
N = 41Sham− 0.139− 0.006− 0.191− 0.142− 0.0410.074
Log SDNN (ms)SM− 0.1880.077− 0.081− 0.0010.114− 0.024
N = 41Sham− 0.160− 0.041− 0.263− 0.062− 0.145− 0.024
SBP (mmHg)SM0.1410.0810.0870.2090.1370.343
N = 30Sham0.1650.2470.3360.4120.5090.581
DBP (mmHg)SM− 0.010− 0.0220.015− 0.0940.0970.024
N = 30Sham0.1530.0940.1900.0200.3430.266
MBP (mmHg)SM0.0400.0120.046− 0.0520.1560.165
N = 30Sham0.1490.1380.1870.0580.4280.380
LF-SBP (mm2Hg)SM0.2780.1420.1640.0620.007− 0.236
N = 30Sham0.181− 0.0380.0900.3790.0430.058
  1. Notes
  2. - Statistically significant correlations at p < 0.006 (Bonferroni correction) are bold faced
  3. - † Spearman’s correlation coefficients
  4. - Pearson’s correlation coefficients unless contrary mention
  5. - For correlations between blood pressure and distal PPT results were based (i) on 27 subjects for Post 1 - Baseline and Post 2 - Baseline and (ii) on 25 subjects for Post 3 - Baseline
  6. Abbreviations:
  7. SM Spinal manipulation, RRi intervals between normal beats; Log logarithm with base 10; HF high frequency; HF normalized unit: HF/(HF + LF)×100; LF low frequency; RMSSD root mean square of the successive differences between normal heartbeats; SDNN standard deviation of the inter beat interval of normal sinus beats; SBP systolic blood pressure; DBP diastolic blood pressure; MBP mean blood pressure; PPT pressure pain threshold in kilopascal