Diagnostic Studies | |||||
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Author(s), Year | Design, Sample size (n) | Case definition | Index test | Reference Standard | Validity |
McAviney, 2005 [45] | Study of criterion validity (Phase 1 for AWB and Phase 2 for ARA) n = 277 | Cervical x-rays from randomly selected patients from Summer Hill Chiropractic Outpatient Clinic (Macquarie University, Australia), over 7 years Exclusion: moderate to severe degenerative changes; cervical spine with obvious lordosis and kyphosis; history of trauma. | Sagittal cervical alignment on x-ray films using posterior tangent method: ARA of cervical lordosis from C2-C7, AWB of the head (horizontal distance of posterior superior body of C2 compared to vertical line from posterior inferior body of C7) Partitioned into categories with increments of 5° | Presence/Absence of cervical complaints: patients’ records, history in intern’s radiology report and x-ray referral slip | ARA: Cervical complaint: 9.6° Non-cervical complaint: 23.4° ARA < 20° (to identify cervical complaint) Sn: 0.724 Sp: 0.737 AUC: 0.803 AWB: Cervical complaint: 21.3 mm Non-cervical complaint: 21.1 mm NS difference between groups |
McGregor, 1995 [46] | Phase 2 study n = 512 | New patients, > 18 YO, Canadian Memorial Chiropractic College outpatient clinic, neck and/or head pain, excluding patients diagnosed with pathology Asymptomatic subjects from small normative group from a different study Assessed for intersegmental clinical hypermobility: mobility of a given motion unit in the cervical spine which is excessive and is accompanied by local and/or peripheral symptoms | AP, lateral, AP open-mouth, forward flexion and extension cervical radiographs Including history and physical examination findings summarized in a standardized case report form | AP, lateral, AP open-mouth cervical radiographs Including history and physical examination findings summarized in a standardized case report form | With flexion-extension radiographs (3 raters): Sn: 0.65–0.89 Sp: 0.49–0.92 Without flexion-extension radiographs (3 raters): Sn: 0.11–0.91 Sp: 0.64–0.99 |