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Table 5 Summary of findings for studies of unacceptable quality

From: The global summit on the efficacy and effectiveness of spinal manipulative therapy for the prevention and treatment of non-musculoskeletal disorders: a systematic review of the literature

Author,

Year

Origin of study sample

Study population

Interventions

Time of follow-up

Outcome variables

Results from authors – SMT superior to control

Infantile Colic

 Miller, 2012 [89]

Chiropractic teaching clinic at Anglo-European College of Chiropractic

Infants with colic

SMT vs. Parent-blinded control

10 days or at discharge

24 h crying diary, Global improvement scale

Yes

 Wiberg, 1999 [85]

Suburb of Copenhagen, Denmark

Infants with colic

SMT vs. Usual care

12 to 15 days

24 h crying diary, parents’ subjective evaluation of change

Yes

Hypertension

 Bakris, 2007 [88]

Unknown, USA

Adults with hypertension

SMT vs. Sham

8 weeks

Blood pressure

Yes

 Molins-Cubero, 2014 [79]

Physiotherapy private practice; Madrid, Spain

Women with primary dysmenorrhea

SMT vs. Sham

Post-intervention

VAS

Yes

 Kokjohn, 1992 [83]

Local community, local chiropractors or gynecologists; Illinois, USA

Women with primary dysmenorrhea

SMT vs. Sham

1-h post-intervention

VAS or MDQ

Yes

Migraine

 Chaibi, 2017 [82]

University hospital, general practitioners and community in Oslo Counties, Norway

Adults with migraine

SMT vs. Control

Immediately, 3 months

Migraine days, headache index

Yes

    

6 and 12 months

Migraine duration or intensity

No

 Tuchin, 2000 [86]

Radio and newspaper advertisements in Sydney region

Adults with migraine

SMT vs. Control

6 months

Frequency, duration, disability, use of medication

Yes

     

Intensity, associated symptoms

No

 Parker, 1978 [78]

Unknown; Australia

Adults with migraine

SMT vs. Mobilization

2 months

Duration, intensity, disability

No

Irritable Bowel Syndrome

 Qu, 2012 [90]

Outpatient department from Zhongda Hospital

Adults with irritable bowel syndrome

SMT vs. Drug

Post-intervention

VAS, Bowel symptom scale

Yes

  1. Legend: SMT spinal manipulative therapy, MDQ Moos’ menstrual distress questionnaire, mths months, NS non-significant, VAS visual analog scale