TY - JOUR AU - Nim, Casper Glissmann AU - Weber, Kenneth Arnold AU - Kawchuk, Gregory Neill AU - O’Neill, Søren PY - 2021 DA - 2021/02/24 TI - Spinal manipulation and modulation of pain sensitivity in persistent low back pain: a secondary cluster analysis of a randomized trial JO - Chiropractic & Manual Therapies SP - 10 VL - 29 IS - 1 AB - Pain hypersensitivity can be assessed using Quantitative Sensory Testing (QST) and is associated with persistent low back pain. Spinal manipulation appears to modify pain hypersensitivity, and this could function as one mechanism leading to clinical improvements. In the current study, we applied a comprehensive QST battery to assess pain sensitivity in a cohort of low back pain patients before and after spinal manipulation to improve our understanding of the association between QST and clinical improvements. This study addresses two questions: Are clinical improvements following spinal manipulation in low back pain patients contingent on pain hypersensitivity, and does pain sensitivity change following spinal manipulation? SN - 2045-709X UR - https://doi.org/10.1186/s12998-021-00367-4 DO - 10.1186/s12998-021-00367-4 ID - Nim2021 ER -