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Table 4 Baseline differences between each latent profile derived cluster using QST in chronic low back pain

From: Spinal manipulation and modulation of pain sensitivity in persistent low back pain: a secondary cluster analysis of a randomized trial

Variable Sensitized Not sensitized p-value
Low back pain intensity 6.17 (5.00, 7.25) 5.33 (4.33, 6.67) 0.07
Oswestry disability index 30 (20, 40) 26 (16, 34) 0.1
sex    0.1
Female 22 (58%) 36 (40%)  
Male 16 (42%) 53 (60%)  
Age 44 (39, 50) 47 (39, 54) 0.2
Depression 3.75 (2.12, 5.50) 4.00 (1.00, 6.00) 0.8
Catastrophization 4.00 (2.00, 6.00) 3.75 (2.00, 5.50) 0.6
Anxiety 5 (1, 7) 4 (2, 5) 0.3
Regional pressure pain threshold 266 (194, 387) 586 (399, 697) < 0.001
Regional heat pain threshold 40.6 (38.9, 43.2) 42.6 (40.0, 45.6) < 0.01
Remote pressure pain threshold 13 (10, 17) 14 (10, 18) 0.4
Remote pressure pain tolerance 35 (29, 43) 59 (50, 75) < 0.001
Temporal summation 0.62 (0.08, 1.23) 0.90 (0.27, 1.52) 0.1
Conditioned pain modulation 3 (− 1, 6) 5 (0, 12) 0.03
  1. Median values (Interquartile range) or count (frequency) in the two groups derived from latent profile analysis. Univariate statistical tests performed: Wilcoxon rank-sum test or chi-squared test of independence. QST = Quantitative sensory pain testing