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Table 4 Baseline differences between each latent profile derived cluster using QST in chronic low back pain

From: Spinal manipulation and modulation of pain sensitivity in persistent low back pain: a secondary cluster analysis of a randomized trial

Variable

Sensitized

Not sensitized

p-value

Low back pain intensity

6.17 (5.00, 7.25)

5.33 (4.33, 6.67)

0.07

Oswestry disability index

30 (20, 40)

26 (16, 34)

0.1

sex

  

0.1

Female

22 (58%)

36 (40%)

 

Male

16 (42%)

53 (60%)

 

Age

44 (39, 50)

47 (39, 54)

0.2

Depression

3.75 (2.12, 5.50)

4.00 (1.00, 6.00)

0.8

Catastrophization

4.00 (2.00, 6.00)

3.75 (2.00, 5.50)

0.6

Anxiety

5 (1, 7)

4 (2, 5)

0.3

Regional pressure pain threshold

266 (194, 387)

586 (399, 697)

< 0.001

Regional heat pain threshold

40.6 (38.9, 43.2)

42.6 (40.0, 45.6)

< 0.01

Remote pressure pain threshold

13 (10, 17)

14 (10, 18)

0.4

Remote pressure pain tolerance

35 (29, 43)

59 (50, 75)

< 0.001

Temporal summation

0.62 (0.08, 1.23)

0.90 (0.27, 1.52)

0.1

Conditioned pain modulation

3 (− 1, 6)

5 (0, 12)

0.03

  1. Median values (Interquartile range) or count (frequency) in the two groups derived from latent profile analysis. Univariate statistical tests performed: Wilcoxon rank-sum test or chi-squared test of independence. QST = Quantitative sensory pain testing