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Table 5 Within- and between-cluster changes in low back pain intensity and disability for each latent profile derived cluster after spinal manipulation

From: Spinal manipulation and modulation of pain sensitivity in persistent low back pain: a secondary cluster analysis of a randomized trial

Outcomes

 

Baseline to Post-SM

Baseline to Follow up

  

Sensitized

Not sensitized

Sensitized

Not sensitized

Low back pain intensity (NRS)

Within-group changes

−0.59(− 1.14 to −0.04)*

−0.75(− 1.11 to −0.39)*

−0.92(− 1.46 to − 0.37)*

− 0.75(− 1.11 to − 0.39)*

Between-group differences

− 0.16(− 0.82 to 0.5)

0.21(− 0.44 to 0.87)

Disability (ODI)

Within-group changes

−5.67(− 8.79 to −2.54)*

−5.57(− 7.64 to − 3.49)*

−7.88(− 10.98 to − 4.77)*

− 5.57(− 7.64 to − 3.49)*

Between-group differences

0.1(− 3.65 to 3.85)

2.26(− 1.48 to 5.99)

  1. Mean within-cluster changes (95% Confidence intervals) and mean between-cluster differences (95% confidence intervals) from baseline to post-SM and follow up, respectively, in the two groups derived from latent profile analysis. NRS = Numerical pain rating score [0–10], ODI = Oswestry disability index [0–100], * = p-value < 0.05