Figure 1

A–D Mean estimated trajectories (A) and separate trajectories per class, with individual trajectories of all patients (B–D). The X-axis represents the measurement moments (1 = baseline, 2 = 6 weeks, 3 = 12 weeks, 4 = 18 weeks, and 5 = 26 weeks follow-up). The Y-axis represents the NRS mean group scores (red line: not improved patients (26.5%), blue line: improved patients (46.0%), green line: patients with low baseline pain levels (27.5%)). In (A), squared lines represent sample trajectories, triangular lines represent estimated trajectories. B–D show the estimated trajectory with the individual trajectories of all individual patients for not improved patients (B), improved patients (C), and patients with low baseline NRS (D) separately. Grey lines represent the individual trajectories of all patients