|
Development dataset 1 (n = 249)
|
|---|
|
MS
|
n (DYS)
|
Sensitivity (%)
|
Specificity (%)
|
PPV (%)
|
NPV (%)
|
Youden’s index
|
|---|
|
8
|
229
|
100.0
|
13.0
|
41.5
|
100.0
|
0.110
|
|
9
|
224
|
100.0
|
16.2
|
42.4
|
100.0
|
0.130
|
|
10
|
220
|
100.0
|
18.8
|
43.2
|
100.0
|
0.162
|
|
11
|
218
|
100.0
|
20.1
|
43.6
|
100.0
|
0.188
|
|
12
|
205
|
100.0
|
28.6
|
46.3
|
100.0
|
0.201
|
|
13
|
201
|
100.0
|
31.2
|
47.3
|
100.0
|
0.286
|
|
14
|
193
|
100.0
|
36.4
|
49.2
|
100.0
|
0.312
|
|
15
|
180
|
98.9
|
44.2
|
52.2
|
98.6
|
0.364
|
|
16
|
173
|
98.9
|
48.7
|
54.3
|
98.7
|
0.431
|
|
17
|
159
|
96.8
|
56.5
|
57.9
|
96.7
|
0.476
|
|
18
|
146
|
95.8
|
64.3
|
62.3
|
96.1
|
0.533
|
|
19
|
140
|
94.7
|
67.5
|
64.3
|
95.4
|
0.601
|
|
20
|
133
|
90.5
|
69.5
|
64.7
|
92.2
|
0.623
|
|
21
|
122
|
86.3
|
74.0
|
67.2
|
89.8
|
0.600
|
|
22
|
109
|
81.1
|
79.2
|
70.6
|
87.1
|
0.603
|
|
23
|
103
|
75.8
|
79.9
|
69.9
|
84.2
|
0.603
|
|
24
|
92
|
70.5
|
83.8
|
72.8
|
82.2
|
0.557
|
|
25
|
84
|
63.2
|
84.4
|
71.4
|
78.8
|
0.543
|
|
26
|
74
|
60.0
|
89.0
|
77.0
|
78.3
|
0.476
|
|
27
|
67
|
55.8
|
90.9
|
79.1
|
76.9
|
0.490
|
- MS, MAINTAIN Score (emphasis represent recommended thresholds); n(DYS), number of individuals classified as dysfunctional by the MAINTAIN instrument at that threshold; PPV, Positive Predictive Value; NPV, Negative Predictive Value
