Table 2 Diagnostic accuracy in development dataset 1 using each level of the MAINTAIN instrument as possible discrimination thresholds to classify dysfunctional patients (96 individuals were classified as dysfunctional by the original instrument in this sample)
Development dataset 1 (n = 249) | ||||||
|---|---|---|---|---|---|---|
MS | n (DYS) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Youden’s index |
8 | 229 | 100.0 | 13.0 | 41.5 | 100.0 | 0.110 |
9 | 224 | 100.0 | 16.2 | 42.4 | 100.0 | 0.130 |
10 | 220 | 100.0 | 18.8 | 43.2 | 100.0 | 0.162 |
11 | 218 | 100.0 | 20.1 | 43.6 | 100.0 | 0.188 |
12 | 205 | 100.0 | 28.6 | 46.3 | 100.0 | 0.201 |
13 | 201 | 100.0 | 31.2 | 47.3 | 100.0 | 0.286 |
14 | 193 | 100.0 | 36.4 | 49.2 | 100.0 | 0.312 |
15 | 180 | 98.9 | 44.2 | 52.2 | 98.6 | 0.364 |
16 | 173 | 98.9 | 48.7 | 54.3 | 98.7 | 0.431 |
17 | 159 | 96.8 | 56.5 | 57.9 | 96.7 | 0.476 |
18 | 146 | 95.8 | 64.3 | 62.3 | 96.1 | 0.533 |
19 | 140 | 94.7 | 67.5 | 64.3 | 95.4 | 0.601 |
20 | 133 | 90.5 | 69.5 | 64.7 | 92.2 | 0.623 |
21 | 122 | 86.3 | 74.0 | 67.2 | 89.8 | 0.600 |
22 | 109 | 81.1 | 79.2 | 70.6 | 87.1 | 0.603 |
23 | 103 | 75.8 | 79.9 | 69.9 | 84.2 | 0.603 |
24 | 92 | 70.5 | 83.8 | 72.8 | 82.2 | 0.557 |
25 | 84 | 63.2 | 84.4 | 71.4 | 78.8 | 0.543 |
26 | 74 | 60.0 | 89.0 | 77.0 | 78.3 | 0.476 |
27 | 67 | 55.8 | 90.9 | 79.1 | 76.9 | 0.490 |