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Table 1 Aetiology of Hypothyroidism

From: The biopsychosocial model and hypothyroidism

Category Cause
Autoimmune Hashimoto's Thyroiditis, Reidels Disease, previous Graves disease, de Quervains thyroiditis, postpartum thyroiditis, Downs syndrome, family history of autoimmune disease or associated disorders (vitiligo, adrenal insufficiency, diabetes mellitus type-1, Sjogren's, coeliac disease), Turner's syndrome, Multiple Sclerosis, primary pulmonary hypertension
Nutritional Iodine deficiency, excess intake of goitrogens, excessive iodine intake
Environmental Radiation Exposure, exposure to polybrominated and polychlorinated biphenyls and resorcinol
Iatrogenic Radioactive iodine therapy, medical radiation exposure, total or subtotal thyroidectomy, drugs impairing thyroid function (amiodarone, thalidomide, betaroxine, lithium carbonate, stavudine, aminoglutethimide)
Hypothalamic Hypothalamic or suprasellar mass, history of hypothalamic radiotherapy or surgery, disorders causing hypothalamic dysfunction (eg sarcoidosis, heamochromatosis)
Pituitary Known pituitary tumour, other elements of hypopituitarism, manifestations of sellar mass, history of pituitary surgery or radiotherapy, history of head trauma
Other Postpartum status