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Table 1 Symptoms and Signs of Pituitary Hormone Deficiency. With permission from the Pituitary Society

From: Nonfunctioning pituitary macroadenoma: a case report from the patient perspective

Pituitary Hormone Target Organs Effect of Deficiency
ACTH Adrenal glands: cortisol and DHEA Fatigue, low sodium in blood, weight loss, skin pallor
TSH Thyroid gland: thyroid hormone Fatigue, weight gain, dry skin, sensitivity to cold, constipation
LH and FSH in Women Ovaries: estrogen, progesterone; ovulation Loss of periods, loss of sex drive, infertility
LH and FSH in Men Testes: testosterone, sperm production Loss of sex drive, erectile dysfunction, impotence, infertility
GH in Children & Adolescents Bone, muscle, fat Lack of growth (height); increased body fat, failure to achieve normal peak bone mass
GH in Adults Whole body Poor quality of life, increased body fat, decreased muscle and bone mass
PRL Breast Inability to breast feed
Oxytocin Breast, Uterus Complete deficiency could make breast feeding difficult
Antidiuretic hormone (vasopressin) Kidney Frequent urination (day & night), dilute urine, excessive thirst