Table 2 Description of seven articles authored or co-authored by FR Carrick reporting on effect or benefit of the Functional Neurology approach and using an appropriate study design
1st Author [Ref] Year Journal | Condition studied | Study subjects : - Type - Age (range) - Origin - Number (analyzed/included) | - Intervention - Control (other than sham) - Sham | - Outcome variables | When was it assessed ? | - Ethics approval (with a clear mention of its origin) - Trial registration | - Conflict of Interest (CoI) (reported or supposed) - Funding |
|---|---|---|---|---|---|---|---|
Carrick [31] 2018 Front Neurol | Autism Spectrum Disorder (ASD) | - ASD children - 4-17 years -? - 34/83 | - Mente Autism Device - NA - Sham Device | - qEEG - ASD questionnaires - Posturography - a) Delta-alpha ratio - b) Power ratio index - c) Brain symmetry index (a,b and c collected through qEEG) - NIH Stroke Scale | - Before - After 12 weeks | - « our Institutional Review Board » - NCT02773303 | - Reported no CoI - Carrick Institute - Plasticity Brain Center - Neurotech International Limited |
Carrick[30] 2016 Front Neurol | Stroke | - Adults with acute middle cerebral artery ischemic stroke - > 39 years - “our intensive care unit” - 34/34 | - Aspirine + 3 repetitions of saccades/ smooth pursuits, 3 treatments a day - Aspirine - NA | - Before, upon admission - After 7 days of treatment | - “our Institution” - No | - Reported no CoI - Carrick Institute - Plasticity Brain Center | |
Pagnacco [29] 2015 Biomed Sci Instrum | Postural Balance | - Adults - 46 - Normal subjects − 39/? | - Toned based stimulation - own control -? | - Stability score | - Suring the experiment | - Yes “the Carrick Institute for Graduate Study IRB#1 - Neurology” - No | - Not reported - Not reported |
Carrick [20] 2013 Funct Neurol Rehabil Ergon | Postural Balance | Study 1: - Healthy Adults - 20-60 years -Volunteers through advertisements - 52/52 Study 2: - Healthy adults - 20-61 years - Volunteers through advertisements - 56/56 | Both studies: - Whole body rotation over 40s for all groups - Each group (4 groups per study) differed in terms of pitch and yaw planes during whole body rotation - NA | Study 1: 8 posturographic measures Study 2: 6 posturographic measures | Both studies: - Before - Immediately after - After 1 day - After 1 week | - “our IRB” - NA | - Not reported - Not reported |
Daubeny [21] 2010 Int J Disabil Hum Dev | Brain Function | - Healthy adults -? -? - 62/ 62 | - Upper extremity manipulations - NA - Upper extremity manipulation with unloaded activator | - Blind-spot size | - Before - Immediately after | - No - No | - Reported no CoI but at least 2 authors are known to have business interest in relation to the topic. - No |
Carrick [32] 2007 J Altern Complement Med | Postural Balance | - Adult healthy volunteers - 22-74 years -? - 266/270 (210 + 60) | - 9 groups of listening to different types of music (several interventions, probably also serving as controls) - White noise (unclear if considered as sham) | - Force platform (CAPS score) | - Before - After 10 min - After 1 week - After 1 month | - “Our institutional review board” - NCT00121693 | - Reported no CoI, but reported that two authors owned two patents on the posturographic device used in the study. - Carrick Institute |
Carrick [7] 1997 J Manipulative Physiol Ther | Brain Function | Phase II: - Adult volunteers -? - enrolled in various postdoctoral programs - 20 | (Unusual design, study subjects requiring ‘correct’ treatment were either treated ‘correctly’ or ‘incorrectly’) - Manipulation of C2 at the ‘correct’ side - Manipulation of C2 at the ‘incorrect’ side | - Blind spot size | - Before - After | - No - NA (not possible/common at this time) | - Not reported - Not reported |