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Table 4 Responder analysis

From: Multidisciplinary integrative care versus chiropractic care for low back pain: a randomized clinical trial

% Pain reduction

Treatment groups

Group differences

Chiropractic Care (%)

Integrated care (%)

Chiropractic care minus integrated care

Week 12*

No reduction or increase

17.7

12.9

4.8 (− 5.3 to 15.1)

 ≥ 30%

64.6

72.3

−7.7 (−20.3 to 5.2)

  ≥ 50%

50.0

56.4

−6.4 (−19.9 to 7.4)

  ≥ 75%

15.6

21.8

−6.2 (−16.9 to 4.9)

100%

1.0

5.9

−4.9 (−11.4 to 0.7)

Week 26^

No reduction or increase

26.6

21.6

4.9 (−7.2 to 16.9)

  ≥ 30%

54.3

61.9

−7.6 (−21.1 to 6.3)

  ≥ 50%

28.7

43.3

−14.6 (−27.4 to −1.0)

 ≥ 75%

14.9

18.6

−3.7 (−14.3 to 7.1)

100%

2.1

3.1

−1.0 (−6.8 to 4.7)

Week 52†

No reduction or increase

25.3

16.5

8.8 (−2.9 to 20.5)

  ≥ 30%

50.6

64.9

−14.4 (−27.9 to −0.1)

  ≥ 50%

36.8

48.5

−11.7 (−25.2 to 2.6)

  ≥ 75%

19.5

21.6

−2.1 (−13.6 to 9.7)

 100%

3.4

5.2

−1.7 (−8.4 to 5.2)

  1. Proportion of participants with at least 30, 50, 75, or 100% reduction in pain intensity
  2. *Analysis included 96 participants in Chiropractic care group and 101 in Integrated care group;
  3. ^Analysis included 94 participants in Chiropractic care group and 97 in Integrated care group;
  4. †Analysis included 87 participants in Chiropractic care group and 97 in Integrated care group;