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Table 1 The description of included RCTs in systematic review

From: Effect of ischemic compression on myofascial pain syndrome: a systematic review and meta-analysis

First author, Year, and location

Population enrolled

Groups and Controls

Characteristic of ischemic compression

Observation time point

Index

Tanhan, 2021, Turkey

75 subjects

Exercise group (n = 25), low level laser group (n = 25), manual pressure release group (n = 25)

Repeated pressure and release on MTrP, until no MTrP tension, three days a week for four weeks

Pre and post treatment

BDI, SF-36, Northwick Park Neck Pain Questionnaire

Kashyap, 2018, India

45 females at 18–30 years

Manual pressure release group (n = 15), muscle energy technique group (n = 15) and control group (n = 15)

Gradually increasing pressure until VAS decrease

Pre and post treatment, 5, 10, 15 days after treatment

PPT, VAS, cervical range of rotation, NDI

De Meulemeester, 2016, Belgium

42 female office workers

Dry needling group (n = 20) and manual pressure group (n = 33)

Pressure on MTrP from 10 N/S to highest tolerable level, 60 s, once a week for 4 weeks

Baseline, after 1 treatment and after 4 treatments, 3 months after treatments

Numeric rating scale, NDI, PPT

Sadria, 2017, Iran

64 subjects at 18–50 years

Pressure and release group (n = 32) and muscle energy group (n = 32)

Pressure or tension with thumb or finger over the MTrP

Pre and post treatment

VAS, Cervical lateral flexion ROM, Upper trapezius thickness

Ransone, 2019, USA

30 subjects

Manual compressive at MTrP group (n = 10), manual compressive at close-proximity within 2.5 cm around MTrP group (n = 10) and control group (n = 10) received sham treatment

Moderate pressure 3 times a week for 4 weeks with each treatment session

Pre and post treatment

PPT

Abu-Taleb, 2016, Egypt

45 subjects

Algometer pressure release (n = 15), pressure release group (n = 15), sham ultrasound group (n = 15)

Repeated pressure and release on MTrPs, until no MTrP tension, three days a week for four weeks

Pre and post treatment

PPT, cervical range of motion

Ganesh, 2015, India

90 subjects with 36 males and 54 females at 19–24 years

Cervical mobilization group (n = 30), ischemic compression group (n = 30) and control group (n = 30)

Ischemic compression to upper trapezius muscle for 5 days

Pre and post treatment, 24 h, 5th day and 2 weeks after treatment

PPT, passive cervical lateral flexion

Aguilera, 2009, Spain

66 subjects with 29 males and 37 females

Ischemic compression group (n = 22), ultrasound group (n = 22), control group (n = 22)

Ischemic compression for 60–90 s

Pre and post treatment

Active ROM, Pressure tolerance, Basal Electrical activity

Ziaeifar, 2016, Iran

32 subjects

Standard group using ischemic compression (n = 17) and experiment group using dry needling (n = 14)

Increasing pressure to MTrP for 3 repetitive times, 1 week

Pre and 3 sessions individually and 2 days after treatmennt

NPS, PPT

Alghadir, 2020, Saudi Arabia

60 subjects at 19–38 years

Group A (n = 20) received all exercise containing hot pack, stretching, ischemic compression, and muscle energy, Group B (n = 20) received exercises except ischemic compression, Group C (n = 20) received exercises except muscle energy therapy

Gradually pressure to MTrP for 90 s

Pre and post treatment

VAS, PPT

Oliveira-Campelo, 2013, Portugal

117 subjects from 18 years

Muscle energy group (n = 23), passive stretching group (n = 23), ischemic compression group (n = 24), placebo group (n = 22), wait and see group (n = 25)

Gradually pressure to MTrP for 90 s

Pre and post treatment

Cervical ROM, PPT, Pressure pain perception

Ziaeifar, 2018, Iran

33 females

Ischemic compression group (n = 17) and dry needling group (n = 16)

Ischemic compression for 90 s

Pre and one week after treatment, 2 weeks and 3 months after treatment

VAS, Disability of arm, hand and shoulder, Northwick park neck pain questionnaire

Moraska, 2018, USA

25 subjects at 18–49 years

Ischemic compression massage on MTrP group (n = 12) and sham ultrasound group (n = 13)

Ischemic compression massage for 6 min

Pre and post treatment, upon probe removal

PPT, blood flow

Benito-de-Pedro, 2019, Spain

34 subjects at 18–75 years

Dry needling group (n = 17) and ischemic compression group (n = 17)

Ischemic compression to MTrP for 90 s

Pre and post treatment

PPT, Thermography

Blikstad, 2008, UK

45 subjects at 18–55 years

Activator trigger point group (n = 15), myofascial band therapy (n = 15) and control group received sham ultrasound (n = 15)

A firm thumb pressure in a slow stroking motion in 1 min

Pre and post treatment

NRS, PPT, cervical ROM, degree of lateral flexion

Kannan, 2012, New Zealand

45 subjects of 22 females and 23 males

Therapeutic ultrasound group (n = 15), laser group (n = 15) and ischemic compression group (n = 15)

Ischemic compression continued 1 and 1 half minute using thumb or strong finger

Pre and post treatment

VAS, ROM, Tenderness

Gemmell, 2008, UK

52 subjects

Ischemic compression group (n = 25) and activator trigger point therapy group (n = 27)

Ischemic compression

Pre and post treatment

NPS, PPT

  1. VAS Visual Analogue Scale, BDI Beck Depression Inventory, NRS numeric rating scale of pain, NDI neck disability index, PPT pain pressure threshold, ROM range of motion, PT pain threshold, MTrP myofascial trigger points