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Table 5 Results from studies assessing validity

From: Reliability and validity of physical examination tests for the assessment of ankle instability

Study

Test

Sensitivity

Specificity

Positive LR

Negative LR

Positive PV

Negative PV

Accuracy

Croy et al. [44]

Anterior drawer testa

74 (58, 86)

38 (24, 56)

1.21 (0.86, 1.70)

0.66 (0.32, 1.36)

57.8 (49.3, 65.4)

57.1 (39.4, 73.2)

57.6 (44.8, 69.7)

Anterior drawer testb

83 (64, 93)

40 (27, 56)

1.40 (1.03, 1.90)

0.41 (0.16, 1.08)

36.4 (24.9, 49.1)

44.4 (37.1, 52.1)

56.1 (43.3, 68.3)

Anterior drawer testc

26 (14, 42)

67 (50, 81)

0.79 (0.37, 1.74)

1.09 (0.80, 1.49)

47.4 (29.6, 65.8)

44.7 (37.2, 52.5)

45.5 (33.1, 58.2)

Anterior drawer testc

33 (18, 53)

73 (59, 85)

1.27 (0.59, 2.72)

0.90 (0.64, 1.26)

36.4 (24.8, 49.1)

66.0 (58.1, 73.0)

59.1 (46.3, 71.1)

de César et al. [45]

Ankle external rotation test

20

84.8

1.32

0.94

   

Squeeze test

30

93.5

4.62

0.75

   

Both tests with physical exam

40

84.8

2.63

0.71

   

De Simoni et al. [49]

Tenderness on palpation:

       

Anterior talo-fibular ligament

100 (88, 100)

   

100

  

Calcaneo-fibular ligament

68 (46, 85)

40 (5, 85)

1.13 (0.53, 2.43)

0.80 (0.24, 2.70)

85.0 (72.5, 92.4)

20.0 (6.9, 45.8)

63.3 (43.9, 80.1)

George et al. [48]

Anterior drawer test

59 (36, 79)

100 (78, 100)

0.77

0.44

100

59.1 (46.6, 70.5)

74.3 (56.7, 87.5)

Talar tilt test

54 (23, 83)

100 (85, 100)

1.00

0.45

100

82.8 (71.5, 90.2)

85.7 (69.7, 95.2)

Gomes et al. [16]

Anterior drawer test

50

100

*

0.5

100

56.3

69.6

Anterolateral talar palpation

100

77.8

4.5

0

87.5

100

91.3

Großterlinden et al. [50]

Tenderness on palpation:

       

Anterior inferior tibiofibular

41.7

52.5

0.88

1.11

34.1

59.6

 

Proximal fibula

7.7

93.9

1.26

0.98

16.7

86.7

 

Deltoid ligament

33.3

69.5

1.09

0.96

38.7

63.1

 

Anterior talo-fibular ligament

77.8

27.1

1.07

0.82

38.9

66.7

 

Calcaneo-fibular ligament

61.1

47.5

1.16

0.82

41.5

67.4

 

Syndesmosis Squeeze test

44.4

55.9

1.01

0.99

37.2

62.3

 

External rotation test

55.6

47.5

1.06

0.93

38.5

63.6

 

Drawer test

44.4

67.8

1.38

0.82

44.4

66.7

 

Cotton test

30.6

67.8

0.95

1.02

35.5

61.5

 

Crossed-leg test

13.9

83.1

0.82

1.04

33.3

61.3

 

Hosseinian et al. [53]

Anterior drawer test (anterior talofibular ligament)e

81

80

4.05

0.24

97

30.8

 

Anterior drawer test (anterior talofibular ligament)f

85

63

2.30

0.24

89

54

 

Anterior drawer test (anterior talofibular ligament)g

42

94

7.00

0.62

88

59

 

Inversion stress test (anterior talofibular ligament)e

30

40

0.50

1.75

84

4

 

Inversion stress test (anterior talofibular ligament)f

46

68

1.44

0.79

84

25

 

Inversion stress test (anterior talofibular ligament)g

67

54

1.46

0.61

62

60

 

Inversion stress test (posterior talofibular ligament)e

50

58

1.19

0.86

17

87

 

Inversion stress test (posterior talofibular ligament)f

100

58

2.38

0

2

100

 

Inversion stress test (calcaneofibular ligament)e

50

86

3.57

0.58

93

30

 

Inversion stress test (calcaneofibular ligament)f

65

75

2.60

0.47

73

66

 

Inversion stress test (calcaneofibular ligament)g

63

80

3.15

0.46

95

26

 

Eversion stress test (deltoid ligament)e

70

98

35.00

0.31

75

63

 

Eversion stress test (deltoid ligament)f

17

97

5.67

0.86

25

95

 

Squeeze test (syndesmosis)e

25

99

25.00

0.76

87

79

 

Squeeze test (syndesmosis)f

33

95

6.60

0.71

94

37

 

External rotation stress test (syndesmosis)e

22

97

7.33

0.80

75

78

 

External rotation stress test (syndesmosis)f

33

95

6.6

0.71

37

94

 

Li et al. [52]

Anterior Drawer test

53h, 39.5i

100h, 100i

*

0.95h, 0.61i

  

50h, 68.1i

Anterolateral drawer test

44.7h, 50i

100h, 97.1i

*h, 17.2i

0.55h, 0.51i

  

70.8h, 72.2i

Reverse anterior drawer test

86.8h, 92.1i

91.2h, 88.2i

9.9h, 7.8i

0.14h, 0.09i

  

88.9h, 90.3i

Phisitkul et al. [46]

Anterolateral drawer

100

100

*

0

   

Anterior drawer test

75

50

1.5

0.5

   

Rosen et al. [18]

Manual talar tilt test

49 (34, 64)

82 (69, 90)

2.65 (1.35, 5.20)

0.63 (0.45, 0.88)

   

Sman et al. [47]

Dorsiflexion-external rotation test

71 (55, 83)

63 (49, 75)

1.93 (1.28, 2.94)

0.46 (0.27, 0.79)

60.0 (49.6, 69.5)

73.8 (62.1, 82.9)

66.7 (55.7, 76.4)

Dorsiflexion lunge with compression

69 (53, 82)

41 (28, 56)

1.18 (0.86, 1.64)

0.74 (0.41, 1.35)

48.1 (40.1, 56.2)

63.3 (48.6, 75.9)

53.7 (42.3, 64.7)

Squeeze test

26 (15, 42)

88 (76, 94)

2.15 (0.86, 5.39)

0.84 (0.68, 1.04)

62.5 (39.9, 80.7)

60.6 (55.3, 65.6)

60.9 (49.9, 71.2)

Syndesmosis ligament palpation

92 (79, 97)

29 (18, 42)

1.29 (1.06, 1.58)

0.28 (0.09, 0.89)

50.0 (45.0, 55.0)

82.3 (59.1, 93.8)

56.3 (45.3, 66.9)

Van Dijk et al. [54]

Anterior drawer test

80 (72, 87)

68 (50, 82)

2.48 (1.54, 3.98)

0.29 (0.19, 0.45)

88.7 (83.0, 92.6)

52.1 (41.4, 62.5)

77.3 (69.8, 83.6)

Tenderness on palpation

       

Anterior talo-fibular ligament

100 (97, 100)

32 (18, 49)

1.46 (1.18, 1.81)

0

82.4 (79.1, 85.4)

100

83.8 (77.1, 89.1)

Calcaneo-fibular ligament

49 (40, 58),

76 (60, 89)

2.08 (1.14, 3.78)

0.67 (0.52, 0.85)

87.0 (78.6, 92.4)

32.0 (26.7, 37.5)

55.6 (47.6, 63.5)

Syndesmosis

43 (35, 53)

89 (75, 97)

4.13 (1.60, 10.66)

0.63 (0.52, 0.76)

93.0 (83.7, 97.2)

33.0 (28.9, 37.3)

54.4 (46.3, 62.3)

Medial

52 (43, 62)

58 (41, 74)

1.25 (0.83, 1.88)

0.82 (0.59, 1.14)

80.0 (72.7, 85.8)

27.5 (21.4, 34.5)

53.8 (45.7, 61.7)

Talocrural joint

23 (16, 31)

97 (86, 1.00)

8.72 (1.23, 61.99)

0.79 (0.71, 0.88)

96.6 (79.8, 99.5)

28.2 (26.1, 30.5)

40.6 (32.9, 48.7)

Peroneal tendon

26 (19, 35)

92 (79, 98)

3.32 (1.08, 10.24)

0.80 (0.70, 0.92)

91.4 (77.6, 97.1)

28.0 (25.3, 30.9)

41.9 (34.1, 49.9)

Lateral malleolus

16 (10, 23)

95 (82, 99)

2.96 (0.72, 12.13)

0.89 (0.80, 0.99)

90.5 (69.9, 97.5)

25.9 (23.9, 28.0)

34.4 (27.1, 42.3)

Diffusely lateral

3 (1, 8)

100 (91, 100)

*

0.97 (0.94, 1.00)

100

24.4 (23.8, 25.0)

26.3 (19.6, 33.8)

Supination line

3 (1, 8)

71 (54, 85)

0.11 (0.04, 0.34)

1.36 (1.11, 1.67)

26.7 (10.9, 51.8)

18.6 (15.7, 21.9)

19.4 (13.6, 26.4)

Vaseenon et al. [51]

Anterolateral drawer test

100

66.67

3

0

   

Anterior drawer test

100

66.67

3

0

   
  1. LR: likelihood ratio, PV: predictive value
  2. *Specificity is 100% therefore it is not possible to calculate + LR.. Results in italics indicate numbers that were calculated for this review from provided results in the study
  3. aGrade 2 or above considered positive: 2.3 mm or greater
  4. bGrade 2 or above considered positive: 3.7 mm or greater
  5. cGrade 3 or above considered positive: 2.3 mm or greater
  6. dGrade 3 or above considered positive: 3.7 mm or greater
  7. eSprain + Partial tear + Complete tear
  8. fPartial tear + Complete tear
  9. gComplete tear
  10. hJunior examiner
  11. iSenior examiner